Adrian’s special interest is in breast cancer and mechanisms of resistance to therapy, regulated by hypoxic metabolism and tumour angiogenesis. He runs his research laboratories in the Oncology Department at the Weatherall Institute of Molecular Medicine, on tumour angiogenesis and the role of notch signalling, and hypoxia biology and its regulation. New angiogenesis pathways involving notch signalling and G-coupled receptors have been discovered and therapeutic antibodies have been developed against them, with funding from CRUK.
Learn more about Adrian on his departmental page.