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Professor Ahmed Ahmed

Fellow by Resolution in Obstetrics and Gynaecology

Interests:

I am a Professor of Gynaecological Oncology at the Nuffield Department of Obstetrics and Gynaecology at the University of Oxford and a Consultant Gynaecological Oncology Surgeon at the Oxford Cancer and Haematology Centre and a Fellow of St Hugh’s College. I lead laboratory-based translational research in Gynaecological Oncology. My main research interest is in the surgical, medical and fundamental research into ovarian cancer.

Biography:

I graduated from Ain Shams University in Cairo, Egypt and completed my PhD and Gynaecological Oncology Surgical training at the University of Cambridge. I received my postdoctoral research training at the University of Cambridge and at the University of Texas, M.D. Anderson Cancer Centre in the USA. I was appointed as a Clinical Reader in Oxford in 2010 and became a Medical Research Council Senior Clinical Research Fellow at the Weatherall Institute of Molecular Medicine and Professor of Gynaecological Oncology in 2012.

Publications:

  • Xie X, Bartholomeusz C, Ahmed AA, Kazansky A, Diao L, Baggerly KA, Hortobagyi GN, Ueno NT, ‘Bisphosphorylated PEA-15 sensitizes ovarian cancer cells to paclitaxel by impairing the microtubule-destabilizing effect of SCLIP,’ Mol Cancer Ther, 12 (6), pp. 1099-1111
  • Badgwell DB, Lu Z, Le K, Gao F, Yang M, Suh GK, Bao JJ, Das P et al. ‘The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways,’ Oncogene, 31 (1), pp. 68-79
  • Ahmed AA, Becker CM, Bast RC, ‘The origin of ovarian cancer,’ BJOG, 119 (2), pp. 134-136
  • Ahmed AA, Wang X, Lu Z, Goldsmith J, Le XF, Grandjean G, Bartholomeusz G, Broom B, Bast RC, ‘Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel,’ Cancer Res, 71 (17), pp. 5806-5817
  • Le XF, Mao W, He G, Claret FX, Xia W, Ahmed AA, Hung MC, Siddik ZH, Bast RC, ‘The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells,’ J Natl Cancer Inst, 103 (18), pp. 1403-1422
Position
Fellow by Resolution in Obstetrics and Gynaecology
Subject
Medicine and Biomedical Sciences
Department
Academic - Fellows & Lecturers